|
KMID : 0370020000140000017
|
|
Chung-Ang Journal of Pharmacal Sciences
2000 Volume.14 No. 0 p.17 ~ p.21
|
|
|
Antimicrobial Activity of p-Aminosalicylate Derivatives
|
|
|
|
|
Abstract
|
|
|
|
The 15 synthesized p-aminosalicylate esters derivatives were evaluated for their antimicrobial activities, in vitro, against Mycobacterium phlei (CACC 75432), Staphylococcus aureus (CHA 78311), Bacillus subtilis (CAUCC 310) and Escherichia coli (P32). Bivalent ligand derivatives (1-6) showed weaker activities than their parent p-aminosalicylate(PAS) in vitro. But some of thiouera derivatives (8 and 10) gave stronger activities against Mycobacterium phlei and Staphylococcus aureus than their parent p-aminosalicylate.
|
|
|
KEYWORD
|
|
|
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|